Acute demyelinating encephalomyelitis: Clinical characteristics and outcome
Identifieur interne : 001263 ( Main/Exploration ); précédent : 001262; suivant : 001264Acute demyelinating encephalomyelitis: Clinical characteristics and outcome
Auteurs : Ahmed Farag Elhassanien [Égypte] ; Hesham Abdel Aziz [Égypte]Source :
- Journal of Pediatric Neurosciences [ 1817-1745 ] ; 2013.
Abstract
ADEM, although relatively uncommon, is probably under-recognized.
To spotlight the clinical profile and therapeutic outcome of children with ADEM.
This is a prospective study of patients with ADEM who were admitted to the Pediatric Departments in Aladan and Alfarawanya Hospitals in Kuwait, from January 2009 to January 2011. Clinical, microbiological and radiological data were analyzed.
Of 48 patients presented with acute neurological symptoms and signs, 21 patients fulfilled criteria for ADEM. 80.95% of cases were presenting in winter and spring, 57% of patients had a history of upper respiratory tract illness. The commonest presentations were motor deficits, convulsions and altered consciousness. CSF virology studies showed herpes simplex virus (HSV) and Epstein-Barr virus (EBV) (3 patients) whereas nasal and nasopharyngeal swab showed evidence of influenza H1N1 virus (1 patient). Brain MRI was performed in all patients and revealed multiple hyperintense supratentorial brain lesions on T2/FLAIR images. 85.7% of patients had cortical and/or subcortical white matter lesions which were bilateral and asymmetric in location and size.
ADEM although rare must be considered in children with acute onset of neurological signs and symptoms and must be distinguished from any acute neurological insult.
Url:
DOI: 10.4103/1817-1745.111418
PubMed: 23772240
PubMed Central: 3680891
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 000938
- to stream Pmc, to step Curation: 000938
- to stream Pmc, to step Checkpoint: 000716
- to stream Ncbi, to step Merge: 000386
- to stream Ncbi, to step Curation: 000386
- to stream Ncbi, to step Checkpoint: 000386
- to stream Main, to step Merge: 001265
- to stream Main, to step Curation: 001263
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Acute demyelinating encephalomyelitis: Clinical characteristics and outcome</title><author><name sortKey="Elhassanien, Ahmed Farag" sort="Elhassanien, Ahmed Farag" uniqKey="Elhassanien A" first="Ahmed Farag" last="Elhassanien">Ahmed Farag Elhassanien</name><affiliation wicri:level="1"><nlm:aff id="aff1">Faculty of Medicine, Elmansoura University, Egypt</nlm:aff><country xml:lang="fr">Égypte</country><wicri:regionArea>Faculty of Medicine, Elmansoura University</wicri:regionArea><wicri:noRegion>Elmansoura University</wicri:noRegion></affiliation></author><author><name sortKey="Aziz, Hesham Abdel" sort="Aziz, Hesham Abdel" uniqKey="Aziz H" first="Hesham Abdel" last="Aziz">Hesham Abdel Aziz</name><affiliation wicri:level="1"><nlm:aff id="aff2">Faculty of Medicine, Benha University, Egypt</nlm:aff><country xml:lang="fr">Égypte</country><wicri:regionArea>Faculty of Medicine, Benha University</wicri:regionArea><wicri:noRegion>Benha University</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">23772240</idno><idno type="pmc">3680891</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680891</idno><idno type="RBID">PMC:3680891</idno><idno type="doi">10.4103/1817-1745.111418</idno><date when="2013">2013</date><idno type="wicri:Area/Pmc/Corpus">000938</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000938</idno><idno type="wicri:Area/Pmc/Curation">000938</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000938</idno><idno type="wicri:Area/Pmc/Checkpoint">000716</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000716</idno><idno type="wicri:Area/Ncbi/Merge">000386</idno><idno type="wicri:Area/Ncbi/Curation">000386</idno><idno type="wicri:Area/Ncbi/Checkpoint">000386</idno><idno type="wicri:doubleKey">1817-1745:2013:Elhassanien A:acute:demyelinating:encephalomyelitis</idno><idno type="wicri:Area/Main/Merge">001265</idno><idno type="wicri:Area/Main/Curation">001263</idno><idno type="wicri:Area/Main/Exploration">001263</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Acute demyelinating encephalomyelitis: Clinical characteristics and outcome</title><author><name sortKey="Elhassanien, Ahmed Farag" sort="Elhassanien, Ahmed Farag" uniqKey="Elhassanien A" first="Ahmed Farag" last="Elhassanien">Ahmed Farag Elhassanien</name><affiliation wicri:level="1"><nlm:aff id="aff1">Faculty of Medicine, Elmansoura University, Egypt</nlm:aff><country xml:lang="fr">Égypte</country><wicri:regionArea>Faculty of Medicine, Elmansoura University</wicri:regionArea><wicri:noRegion>Elmansoura University</wicri:noRegion></affiliation></author><author><name sortKey="Aziz, Hesham Abdel" sort="Aziz, Hesham Abdel" uniqKey="Aziz H" first="Hesham Abdel" last="Aziz">Hesham Abdel Aziz</name><affiliation wicri:level="1"><nlm:aff id="aff2">Faculty of Medicine, Benha University, Egypt</nlm:aff><country xml:lang="fr">Égypte</country><wicri:regionArea>Faculty of Medicine, Benha University</wicri:regionArea><wicri:noRegion>Benha University</wicri:noRegion></affiliation></author></analytic><series><title level="j">Journal of Pediatric Neurosciences</title><idno type="ISSN">1817-1745</idno><idno type="eISSN">1998-3948</idno><imprint><date when="2013">2013</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec id="st1"><title>Background:</title><p>ADEM, although relatively uncommon, is probably under-recognized.</p></sec><sec id="st2"><title>Objectives:</title><p>To spotlight the clinical profile and therapeutic outcome of children with ADEM.</p></sec><sec id="st3"><title>Materials and Methods:</title><p>This is a prospective study of patients with ADEM who were admitted to the Pediatric Departments in Aladan and Alfarawanya Hospitals in Kuwait, from January 2009 to January 2011. Clinical, microbiological and radiological data were analyzed.</p></sec><sec id="st4"><title>Results:</title><p>Of 48 patients presented with acute neurological symptoms and signs, 21 patients fulfilled criteria for ADEM. 80.95% of cases were presenting in winter and spring, 57% of patients had a history of upper respiratory tract illness. The commonest presentations were motor deficits, convulsions and altered consciousness. CSF virology studies showed herpes simplex virus (HSV) and Epstein-Barr virus (EBV) (3 patients) whereas nasal and nasopharyngeal swab showed evidence of influenza H1N1 virus (1 patient). Brain MRI was performed in all patients and revealed multiple hyperintense supratentorial brain lesions on T2/FLAIR images. 85.7% of patients had cortical and/or subcortical white matter lesions which were bilateral and asymmetric in location and size.</p></sec><sec id="st5"><title>Conclusion:</title><p>ADEM although rare must be considered in children with acute onset of neurological signs and symptoms and must be distinguished from any acute neurological insult.</p></sec></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Banwell, B" uniqKey="Banwell B">B Banwell</name></author><author><name sortKey="Kennedy, J" uniqKey="Kennedy J">J Kennedy</name></author><author><name sortKey="Sadovnick, D" uniqKey="Sadovnick D">D Sadovnick</name></author><author><name sortKey="Arnold, Dl" uniqKey="Arnold D">DL Arnold</name></author><author><name sortKey="Magalhaes, S" uniqKey="Magalhaes S">S Magalhaes</name></author><author><name sortKey="Wambera, K" uniqKey="Wambera K">K Wambera</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Leake, Ja" uniqKey="Leake J">JA Leake</name></author><author><name sortKey="Albani, S" uniqKey="Albani S">S Albani</name></author><author><name sortKey="Kao, As" uniqKey="Kao A">AS Kao</name></author><author><name sortKey="Senac, Mo" uniqKey="Senac M">MO Senac</name></author><author><name sortKey="Billman, Gf" uniqKey="Billman G">GF Billman</name></author><author><name sortKey="Nespeca, Mp" uniqKey="Nespeca M">MP Nespeca</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mcalpine, D" uniqKey="Mcalpine D">D McAlpine</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Murthy, Sn" uniqKey="Murthy S">SN Murthy</name></author><author><name sortKey="Faden, Hs" uniqKey="Faden H">HS Faden</name></author><author><name sortKey="Cohen, Me" uniqKey="Cohen M">ME Cohen</name></author><author><name sortKey="Bakshi, R" uniqKey="Bakshi R">R Bakshi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tenembaum, S" uniqKey="Tenembaum S">S Tenembaum</name></author><author><name sortKey="Chitnis, T" uniqKey="Chitnis T">T Chitnis</name></author><author><name sortKey="Ness, J" uniqKey="Ness J">J Ness</name></author><author><name sortKey="Hahn, Js" uniqKey="Hahn J">JS Hahn</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Oksuzler, Yf" uniqKey="Oksuzler Y">YF Oksuzler</name></author><author><name sortKey="Cakmakci, H" uniqKey="Cakmakci H">H Cakmakci</name></author><author><name sortKey="Kurul, S" uniqKey="Kurul S">S Kurul</name></author><author><name sortKey="Oksuzler, M" uniqKey="Oksuzler M">M Oksuzler</name></author><author><name sortKey="Dirik, E" uniqKey="Dirik E">E Dirik</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kuperan, S" uniqKey="Kuperan S">S Kuperan</name></author><author><name sortKey="Ostrow, P" uniqKey="Ostrow P">P Ostrow</name></author><author><name sortKey="Landi, Mk" uniqKey="Landi M">MK Landi</name></author><author><name sortKey="Bakshi, R" uniqKey="Bakshi R">R Bakshi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Menge, T" uniqKey="Menge T">T Menge</name></author><author><name sortKey="Hemmer, B" uniqKey="Hemmer B">B Hemmer</name></author><author><name sortKey="Nessler, S" uniqKey="Nessler S">S Nessler</name></author><author><name sortKey="Wiendl, H" uniqKey="Wiendl H">H Wiendl</name></author><author><name sortKey="Neuhaus, O" uniqKey="Neuhaus O">O Neuhaus</name></author><author><name sortKey="Hartung, Hp" uniqKey="Hartung H">HP Hartung</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Stonehouse, M" uniqKey="Stonehouse M">M Stonehouse</name></author><author><name sortKey="Gupte, G" uniqKey="Gupte G">G Gupte</name></author><author><name sortKey="Wassmer, E" uniqKey="Wassmer E">E Wassmer</name></author><author><name sortKey="Whitehouse, Wp" uniqKey="Whitehouse W">WP Whitehouse</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Krishna Murthy, Sn" uniqKey="Krishna Murthy S">SN Krishna Murthy</name></author><author><name sortKey="Howard, Sf" uniqKey="Howard S">SF Howard</name></author><author><name sortKey="Michael, Ec" uniqKey="Michael E">EC Michael</name></author><author><name sortKey="Rohit, B" uniqKey="Rohit B">B Rohit</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dale, Rc" uniqKey="Dale R">RC Dale</name></author><author><name sortKey="De Sousa, C" uniqKey="De Sousa C">C de Sousa</name></author><author><name sortKey="Chong, Wk" uniqKey="Chong W">WK Chong</name></author><author><name sortKey="Cox, Tc" uniqKey="Cox T">TC Cox</name></author><author><name sortKey="Harding, B" uniqKey="Harding B">B Harding</name></author><author><name sortKey="Neville, Bg" uniqKey="Neville B">BG Neville</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hynson, Jl" uniqKey="Hynson J">JL Hynson</name></author><author><name sortKey="Kornberg, Aj" uniqKey="Kornberg A">AJ Kornberg</name></author><author><name sortKey="Coleman, Lt" uniqKey="Coleman L">LT Coleman</name></author><author><name sortKey="Shield, L" uniqKey="Shield L">L Shield</name></author><author><name sortKey="Harvey, As" uniqKey="Harvey A">AS Harvey</name></author><author><name sortKey="Kean, Mj" uniqKey="Kean M">MJ Kean</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pohl Koppe, A" uniqKey="Pohl Koppe A">A Pohl-Koppe</name></author><author><name sortKey="Burchett, Sk" uniqKey="Burchett S">SK Burchett</name></author><author><name sortKey="Thiele, Ea" uniqKey="Thiele E">EA Thiele</name></author><author><name sortKey="Hafler, Da" uniqKey="Hafler D">DA Hafler</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yeh, Ea" uniqKey="Yeh E">EA Yeh</name></author><author><name sortKey="Collins, A" uniqKey="Collins A">A Collins</name></author><author><name sortKey="Cohen, Me" uniqKey="Cohen M">ME Cohen</name></author><author><name sortKey="Duffner, Pk" uniqKey="Duffner P">PK Duffner</name></author><author><name sortKey="Faden, H" uniqKey="Faden H">H Faden</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kobayashi, S" uniqKey="Kobayashi S">S Kobayashi</name></author><author><name sortKey="Negishi, Y" uniqKey="Negishi Y">Y Negishi</name></author><author><name sortKey="Ando, N" uniqKey="Ando N">N Ando</name></author><author><name sortKey="Ito, T" uniqKey="Ito T">T Ito</name></author><author><name sortKey="Nakano, M" uniqKey="Nakano M">M Nakano</name></author><author><name sortKey="Togari, H" uniqKey="Togari H">H Togari</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chopra, B" uniqKey="Chopra B">B Chopra</name></author><author><name sortKey="Abraham, R" uniqKey="Abraham R">R Abraham</name></author><author><name sortKey="Abraham, A" uniqKey="Abraham A">A Abraham</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Brass, Sd" uniqKey="Brass S">SD Brass</name></author><author><name sortKey="Caramanos, Z" uniqKey="Caramanos Z">Z Caramanos</name></author><author><name sortKey="Santos, C" uniqKey="Santos C">C Santos</name></author><author><name sortKey="Dilenge, Me" uniqKey="Dilenge M">ME Dilenge</name></author><author><name sortKey="Lapierre, Y" uniqKey="Lapierre Y">Y Lapierre</name></author><author><name sortKey="Rosenblatt, B" uniqKey="Rosenblatt B">B Rosenblatt</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Krupp, Lb" uniqKey="Krupp L">LB Krupp</name></author><author><name sortKey="Banwell, B" uniqKey="Banwell B">B Banwell</name></author><author><name sortKey="Tenembaum, S" uniqKey="Tenembaum S">S Tenembaum</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Égypte</li></country></list><tree><country name="Égypte"><noRegion><name sortKey="Elhassanien, Ahmed Farag" sort="Elhassanien, Ahmed Farag" uniqKey="Elhassanien A" first="Ahmed Farag" last="Elhassanien">Ahmed Farag Elhassanien</name></noRegion><name sortKey="Aziz, Hesham Abdel" sort="Aziz, Hesham Abdel" uniqKey="Aziz H" first="Hesham Abdel" last="Aziz">Hesham Abdel Aziz</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/CovidV2/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001263 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 001263 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= CovidV2
|flux= Main
|étape= Exploration
|type= RBID
|clé= PMC:3680891
|texte= Acute demyelinating encephalomyelitis: Clinical characteristics and outcome
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:23772240" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a CovidV2
| This area was generated with Dilib version V0.6.33. |  |